Dr. Dal Cin

	Department of Pathology
	Brigham and Women's Hospital
	A teaching Affliate of Harvard Medical School
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Name and Present Position:

PAOLA DAL CIN, Cytogeneticist

Address:

Brigham and Women's Hospital, Department of Pathology, 75 Francis Street, Boston, MA

Medical school (including school name, date and degree awarded):

1977 MSci, Biology Faculty, University of Padua, Italy
1986 Ph.D., Biology Faculty, University of Pavia, Italy

Graduate Medical Education:

1986-1988 Cancer Research Scientist, Department of Genetics and Endocrinology, Roswell Park Memorial Institute, Buffalo, NY.
1987-1988 Cancer Research Scientist, The Cancer Center of the Southwest Biomedical Research Insti-tute, Scottsdade, AZ.

Certification;

2005 American Board of Medical Genetics (Clinical Cytogenetics)

Current Academic Appointment:

Associate Professor of Pathology, Harvard Medical School, Boston, MA

Current Medical Staff Appointment:

Associate Cytogeneticist, Brigham and Women's Hospital

Selected Bibliography:

Pentimalli F, Dentice M, Fedele M, Pierantoni GM, Francesco Trapasso F, Cito L , Santoro M, Viglietto G, Dal Cin P, Fusco A. Suppression of HMGA2 protein synthesis could be a tool for therapy of well-differentiated liposarcoma overexpressing HMGA2. Cancer Res 2003; 63(21):7423-7.
Dal Cin P, Thomas A, Weremowicz S. An intragenic rearrangement of HMGA2 is not necessary to occur for lipoma formation. Cancer Genet Cytogenet 2004, 149; 178-179.
Oliveira AM, Hsi BL, Weremowicz S, Perez-Atayde AR, Rosenberg AE, Dal Cin P, Bridge JA, Fletcher JA. USP6 (Tre2) fusion oncogenes in aneurysmal bone cyst. Cancer Res, 2004, 64:1920-1923.
Moore SDP, Herrick SR, Ince TA, Kleinman MS, Dal Cin P, Morton CC, Quade BJ. Uterine leiomyoma with t(10;17) disrupt the histone acetyltransferase MORF. Cancer Res 2004, 64: 5570-5577.
Monti S, Savage KJ, Kutok JL, Feuerhake F, Kurtin P, Mihm M, Bingyan Wu B, Pasqualucci L, Neuberg D, Aguiar RCT, Dal Cin P, Ladd C, Pinkus GS, Salles G, Harris NL, Dalla-Favera R, Habermann TM, Aster JC, Golub TR, Shipp MA. Molecular profiling of diffuse large B-cell lymphoma reveals discrete clusters including one characterized by host inflammatory response. Blood 2005, 105:1851-61.
Oliveira AM, Perez-Atayde AR, Dal Cin P, Gebhardt MC, Rosenberg AE, Bridge JA, Fletcher JA.. Aneurysmal bone cyst variant translocations upregulate USP6 transcription by promoter swapping with the ZNF9, COL1A1, TRAP150 and OMD genes. Oncogene 2005, 24: 3419-3426.
Christacos NC, Quade BJ, Morton CC, Dal Cin P. Uterine leiomyomata with deletions of 1p represent a distinct cytogenetic subgroup associated with unusual histologic features. Genes Chromosomes Cancer, 2006,45:304-312.
Antonescu CR, Nafa K , Segal, NH , Dal Cin P, Ladanyi M. WS-CREB1: A recurrent variant fusion in clear cell sarcoma Association with gastrointestinal location and absence of melanocytic differentiation. Clin Cancer Res, 2006,12:5356-5362
Nucci MR, Harburger D, Koontz J, Dal Cin P, Sklar J. Molecular analysis of the JAZF1/JJAZ1 gene fusion by RT-PCR and fluorescence in situ hybridization in endometrial stromal neoplasms. Am J Surg Path; 2007, 31:65-70.
Soupir CP, Vergilio JA, Dal Cin P, Muzikansky A, Jones DM, Kantarjian H, Hasserjian RP. Philadelphia chromosome positive acute myeloid leukemia: A rare aggressive leukemia with distinct clinicopathologic features from chronic myeloid leukemia in blast crisis. Am J Clin Path 2007, 127:642-650.