Dr. Sacks

	Department of Pathology
	Brigham and Women's Hospital
	A teaching Affliate of Harvard Medical School
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Name and Present Position:

DAVID B. SACKS, Director, Clinical Pathology Residency Training Program

Address:

Brigham and Women's Hospital, Department of Pathology, 75 Francis Street, Boston, MA

Medical School (including school name, date and degree awarded):

1976 MB ChB, University of Cape Town, South Africa

Graduate Medical Education (including dates and institution of internship, residencies, fellowships, etc.):

1977 Rotating Internship, Groote Schuur Hospital, Cape Town, South Africa
1981-85 Resident in Internal Medicine, DC General Hospital and Veterans Administra-tion Hospital,
George-town, Washington, DC
1985-87 Fellow and Chief Fellow in Clinical Chemistry, Washing-ton University School of Medicine, St. Louis, MO

Certification:

1984 American Board of Internal Medicine
1989 American Board of Pathology (Clinical)
1998 Fellowship, Royal College of Pathologists

Current Academic Appointment:

Associate Professor of Pathology, Harvard Medical School, Boston, MA

Current Medical Staff Appointment:

Pathologist, Brigham and Women's Hospital
Director, Clinical Pathology Training Program, Brigham and Women's Hospital

Selected Bibliography:

Joyal JL, Annan RA, Ho YD, Huddleston ME, Carr SA, Hart MJ, Sacks DB. Calmodulin modulates the interaction between IQGAP1 and Cdc42: Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry. J Biol Chem 1997; 272:15419-15425.
Joyal JL, Burks DJ, Pons S, Matter WF, Vlahos CJ, White MF, Sacks DB. Calmodulin activates phosphatidylinosi-tol 3-kinase. J Biol Chem 1997; 272:28183-28186.
Li Z, Kim SH, Higgins JMG, Brenner MB, Sacks DB. IQGAP1 and calmodulin modulate E-cadherin function. J Biol Chem 1999; 274:37885-37892.
Kim SH, Li Z, Sacks DB. E-cadherin-mediated cell-cell attachment activates Cdc42. J Biol Chem 2000; 275:36999-37005.
Li Z, Joyal JL, Sacks DB. Calmodulin enhances the stability of the estrogen receptor. J Biol Chem 2001; 276:17354-17360.
Mataraza JM, Briggs MW, Li Z, Entwistle A, Ridley AJ, Sacks DB. IQGAP1 promotes cell motility and invasion. J Biol Chem 2003; 278:41237-41245.
Li L, Li Z, Sacks DB. The transcriptional activity of estrogen receptor-a is dependent on Ca2+/calmodulin. J Biol Chem 2005; 280:13097-13104.
Li Z, McNulty DE, Marler KJM, Lim L, Hall C, Annan RS, Sacks DB. IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner. J Biol Chem 2005; 280:13871-13878.
Roy M, Li Z, Sacks DB. IQGAP1 is a scaffold for MAP kinase signalling. Mol Cell Biol 2005; in the press.