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Graduate
Medical Education (including dates and institution of internships, residencies,
fellowships, etc.):
1995 PhD (Cancer
Biology), University Texas Hlth Science Center/MD Anderson Cancer Center,
Houston, TX
1995-97 Research Fellow in Molecular and Human Genetics, Baylor College
of Medicine, Houston, TX
1995-97. Trainee in Medical Genetics/Clinical Cytogenetics, Baylor College
of Medicine
1997-99 Research Fellow in Pathology and OB/GYN Reproductive Biology,
Brigham and Women's Hospital, Boston
Certification:
1999 American Board
of Medical Genetics (Clinical Cytogenetics)
Current Academic
Appointment:
Assistant Professor
in Pathology, Harvard Medical School, Boston, MA
Current Medical
Staff Appointment:
Associate Cytogeneticist,
Brigham and Women's Hospital
Director, HMS ABMG
Training Program in Clinical Cytogenetics
Selected Bibliography:
- Cheung VG, Nowak
N, Jang W, Kirsch IR, Zhao S, Chen XN, Furey TS, Kim UJ, Kuo WL, Oliver
M, Conroy J, Kasprzyk A, Massa H, Yonescu R, Sait S, Thoreen C, Snijders
A, Lemyre E, Bailey JA, Bruzel A, Burrill WD, Clegg SM, Collins S, Dhami
P, Friedman C, Hans CS, Herrick S, Lee J, Ligon AH, et al. Integration
of cytogenetic landmarks into the draft sequence of the human genome.
Nature 2001; 409 (6822):953-958.
- Ligon AH, Scott
IC, Takahara K, Greenspan DS, Morton CC. PCOLCE deletion and expression
analyses in uterine leiomyomata. Cancer Genet Cytogenet 2002;137(2):133-7.
- Scherer SW, Cheung
J, MacDonald JR, Osborne LP, Nakabayaski K, Herbrick J-A, Carson AR,
Parker-Katiraee L, Skaug J, Khaja R, Zhang J, Hudek AK, Li M, Haddad
M, Duggan GE, Fernandez BA, Kanematsu E, Gentles S, Christopoulous CC,
Choufani S, Kwasnicka D, Zheng XH, Nusskern D, Zhang Q, Gu Z, Lu F,
Zeesman S, Teshima I, Chitayat D, Shuman C, Weksberg R, Zackai EH, Grebe
TA, Cox SR, Kirtpatrick SJ, Rahman N, Friedman JM, Heng HHQ, Pelicci
PG, Lococo F, Belloni E, Shaffer LG, Pober B, Morton CC, Gusella JF,
Bruns GAP, Korf BR, Quade BJ, Ligon AH, Ferguson H, Higgins AW, Leach
NT, Herrick SR, Lemyre E, Farra CG, Kim H-G, Summers AM, Gripp KW, Roberts
W, Szatmari P, Winsor EJT, Grzeschik K-H, Teebi Ah, Minassian BA, Kere
J, Armengol L, Pugana MA, Estivill X, Wilson MD, Koop BF, Tosi S, Moore
GE, Boright AP, Zlotorynski E, Kerem B, Kroisel PM, Petek E, Oscier
DG, Mould SJ, Dohner H, Dohner K, Rommens JM, Vincent JB, Venter JC,
Li PW, Mural RJ, Adams MD, Tsui L-C. Human chromosome 7: DNA sequence
and biology. Science 2003;300(5620):767-72.
- Gross KL, Neskey
DM, Manchanda N, Weremowicz S, Kleinman M, Nowak RA, Ligon AH, Rogalla
P, Drechsler K, Bullerdiek J, Morton CC: HMGA2 expression in uterine
leiomyomata and myometrium: Quantitive analysis ans tissue culture studies.
Genes Chrom Cancer 2003;38(1):68-79.
- Ligon AH, Morton
CC, Bieber FR, Fletcher JA, Giersch AB, Lee C, Sandstrom M, Weremowicz
S, Xiao S, Dal Cin P. Reporting of Diagnostic Cytogenetic Results. In:
Drapoli NC, Haines JL, Korf BR, Morton CC, Seidman CE, Seidman JG, Smith
DR, editors. Current Protocols in Human Genetics. Wiley & Sons,
Rockville, MD; 2004, Supplement 43, A.1D.1 - A.1D.27.
- Ligon AH. Educational
Insight: Telomeres and Telomerase. Atlas of Genetics and Cytogenetics
in Oncology and Haematology. Posted: June 2004.
- Christacos
NC, Ligon AH, Morton CC. Genetics of uterine leiomyomata. In: Sciarra
JJ, (editor) Gynecology and Obstetrics. Chicago: Lippincott-Raven Press;
2004; 5,Chapter 96.
- *Ligon
AH, *Moore SD, Parisi MA, Mealiffe ME, Harris DJ, Ferguson HL, Quade
BJ, Morton CC. Constitutional rearrangement of the architectural factor
HMGA2: a novel human phenotype including overgrowth and lipomas. Am
J Hum Genet 2005; 76(2):340-8. (*Contributed equally)
- Ligon AH, DeAngelo
DJ, Atkins L, Dal Cin P. Isochromosome of a deleted 20q may be a relatively
common abnormality in myeloid malignancies. Cancer Genet Cytogenet 2005;
162:89-91.
- Kim H-G, Higgins
A, Herrick SR, Nicholson L, Kutsche K, Ligon AH, Harris DJ, MacDonald
ME, Bruns GAP, Morton CC, Quade BJ, Gusella JF. Candidate loci for Zimmermann-Laband
syndrome at 3p14.3. Am J Med Genet A 2007; Jan 15;143(2):107-11.
- Quintero-Rivera
F, Chan A, Donovan D, Gusella JF, Ligon AH. Disruption of a Synaptotagmin
(SYT14) associated with neurodevelopmental abnormalities. Am J Med Genet
A. 2007; Mar 15;143(6):558-63.
- Leach NT, Sun Y,
Michaud S, Zheng Y, Ligon KL, Ligon AH, Sander T, Korf BR, Lu W, Harris
DJ, Gusella JF, Maas RL, Quade BJ, Cole AJ, Kelz MB, Morton CC. Disruption
of diacylglycerol kinase delta (DGKD) associated with seizures in humans
and mice. Am J Hum Genet 2007; (80)792-799.
- *Lu W, *Quintero-Rivera
F, Fan Y, Alkuraya F, Donovan DJ, Xi Q, Turbe-Doan A, Li Q, Campbell
CG, Shanske AL, Sherr E, Ahmad A, Peters R, Rilliet B, Parvex P, Bassuk
AG, Harris DJ, Ferguson H, Kelly C, Walsh C, Gronostajski RM, Devriendt
K, Higgins AW, Ligon AH, Quade BJ, Morton CC, Gusella JF, Maas RL. NFIA
haploinsufficiency is associated with a CNS malformation syndrome and
urinary tract defects. PLoS Genetics 2007:3(5)830-843. (*Contributed
equally)
- Hodge JC, Lawson-Yuen
A, Stoler JM, Ligon AH. Molecular studies of segmental aneusomy: FISHing
for the atypical cry in del(5)(p15.3). Cytogenet and Genome Res, in
press.
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